Table 1 Baseline clinical characteristics of study subjects (n = 249)
| Variables (n = 249) |
AFP < 20 ng/mL (n = 131, 52.6%) |
AFP ≥ 20 ng/mL (n = 118, 47.4%) | p value |
|---|---|---|---|
| Age (year)§ | 60 ± 13 | 59 ± 13 | 0.300 |
| Gender (male), n (%) | 96 (73.3) | 66 (55.9) | 0.005 |
| Race, n (%) | 0.376 | ||
| White/Asian | 72/59 (55.0/45.0) | 58/60 (49.2/50.8) | |
| Cause of HCC, n (%)a | (n = 129) | (n = 117) | 0.384+ |
| HBV | 41 (31.8) | 47 (40.2) | |
| HCV | 20 (15.5) | 11 (9.4) | |
| Alcohol | 26 (20.1) | 18 (15.4) | |
| Mixed (HBV + HCV) | 2 (1.6) | 3 (2.6) | |
| Others | 40 (31.0) | 38 (32.5) | |
| Liver cirrhosis, n (%)b | (n = 96) | (n = 70) | 0.744 |
| Presence | 36 (37.5) | 24 (34.3) | |
| Vascular invasion, n (%)c | (n = 121) | (n = 110) | 0.008+ |
| Absence/presence | 89/32 (73.6/26.4) | 62/48 (56.4/43.6) | |
| AJCC,7th, pTNM stage, n (%)d | (n = 126) | (n = 108) | 0.468+ |
| I | 76 (60.3) | 57 (52.8) | |
| II | 30 (23.8) | 26 (24.1) | |
| III (A/B/C) | 18 (14.3) | 21 (19.4) | |
| IV (A/B) | 2 (1.6) | 4 (3.7) |